Risks and Complications of O2 therapy 1- O2 toxicity Definition: is a condition resulting from the harmful effects of breathing molecular oxygen at high concentration, it is mostly associated with long term oxygen therapy or hyperbaric oxygen therapy (O2 therapy at pressure more than 1 atmosphere). Hyperoxia-induced lung injury has long been recognized as a major limitation to the administration of oxygen in the world of critical care. Breathing 100% oxygen over prolonged periods of time can adversely affect the entire respiratory tract. Factors affecting O2 toxicity a. Oxygen concentration (more than 60%) b. Pressure (normobaric or hyperbaric) c. Time of exposure:
Definition: Oxygen toxicity is a condition that arises from the harmful effects of breathing molecular oxygen at high concentrations. It is primarily associated with long-term oxygen therapy or hyperbaric oxygen therapy (oxygen therapy administered at pressures greater than 1 atmosphere).
Translation and Explanation:
Hyperoxia-induced lung injury has long been recognized as a major limitation to the administration of oxygen in the world of critical care.
Breathing 100% oxygen over prolonged periods of time can adversely affect the entire respiratory tract.
a. Oxygen concentration (more than 60%)
b. Pressure (normobaric or hyperbaric)
c. Time of exposure:
FiO2 > 60% longer than 24 hr
or FiO2 80-100% longer than 12 hr
Long term O2 therapy can produce pulmonary toxicity, ocular toxicity and CNS toxicity.